Motivation for Writing the Paper: Designing Quick and Dirty Applications for Mobiles: Making the case for the utility of HCI principles

This paper discusses the author’s interest in proving that it matters whether someone builds a new application using HCI principles. This is an important issue to discuss because many HCI professionals and researchers think that the conclusion is obvious i.e. that of course it matters and that we should build an application with an end user in mind and then test it with a subset of said users. However, most application developers disagree and actually build their applications using a ‘field of dreams approach’ i.e. if I build it they will come. This issue/disagreement has become especially important to discuss given the advent of mobile applications for the i.phone and other quickly programmed applications. </p

Clinical and molecular epidemiolgy of human rhinoviruses in low to middle income countries

A thesis submitted to the Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the degree of Doctor of Philosophy Johannesburg 2017.Introduction: Human rhinovirus (HRV) is the most prevalent virus detected in children with respiratory symptoms; however, its aetiological role during disease episodes remains unclear as detection of HRV is also ubiquitous among asymptomatic children. We evaluated the clinical epidemiology of HRV-associated disease among children hospitalised with severe and very severe pneumonia together with community control children living in Africa and Southeast Asia. In addition, we explored the associations between the molecular subtyping and nasopharyngeal viral loads of the HRV species and their ability to cause viraemia as potential markers for HRV disease. Methods: Using a case-control study conducted in seven countries, we compared the clinical characteristics of children (1-59 months of age) hospitalised with HRV-associated pneumonia between August 2011 - January 2014 and age-frequency matched controls. Nasopharyngeal swabs from the cases and controls were tested for HRV, together with 27 other respiratory pathogens, with quantitative real-time PCR assays. The 5’ NCR region of the HRV positive samples were sequenced to determine the species/strains of HRV and phylogenetic analysis was performed. Additionally, the blood samples from a limited number of cases (n=210) and controls (n=212) were tested for the presence of HRV viraemia and the 5’ NCR sequence of positive blood samples were further characterised. Results: Overall, HRV detection was 1.45-fold (aOR 95% CI: 1.29-1.62) higher among children hospitalised with pneumonia (24%) compared to controls (21%, P<0.005); including being 2.08-fold (28% vs 18%, aOR 95% CI: 1.75-2.47) more associated with case status among children 12-59 months of age. The HRV-associated cases were younger (13.1 months) than controls with HRV infection (15.4 months, P=0.001) and more likely to be malnourished (30% vs. 12%, P<0.001) and HIV-1 exposed (10% vs. 8%, P=0.046). HRV nasopharyngeal viral load was significantly higher among cases compared to controls (3.7 vs. 3.5 log10 copies/mL, P<0.001). Also, HRV viraemia was 7.02-fold (aOR 95% CI 1.70-28.94) more prevalent among cases (7%) compared to controls (2%, P=0.007). Moreover, HRV nasopharyngeal viral loads ≥4 log10 copies/mL differentiated between viraemia positive and negative cases. There was, however, no difference in the molecular subtyping of the HRV species prevalence among cases (HRV-A:48%; HRV-B:7%; HRV-C:45%) and controls (HRV-A:45%; HRV-B:10%; HRV-C:45%, P=0.496); as well as no evidence of seasonal or temporal clustering of the HRV species over time. Among cases, HRV detection was less likely to be associated with presence of radiographically confirmed pneumonia (40% vs 46%, P=0.001) or hospital stay >3 days (52% vs 61%, P=0.001). It was, however, positively associated with older age (13.1 months vs. 11.3 months, P<0.001) and presence of wheeze (46% vs. 31%, P<0.001) compared to the HRV uninfected cases. HRV was the sole virus detected in the 53% of cases and generally there were no differences in severity or clinical presentation among cases with HRV mono-infections compared to those with HRV-mixed infections. The HRV mono-infections, however, were associated with a 2.83-fold (aOR 95% CI: 1.44-5.53) higher case fatality ratio than cases with HRV and other viral mixed infections (10% vs. 5%, P=0.002). The HRV-associated case fatalities were more likely to have markers of bacterial co-infections compared to the HRV-associated cases that survived. Among the HRV species, HRV-C compared to HRV-A cases were older (12.1 vs. 9.4 months, P=0.033), more likely to present with wheeze (35% vs. 25%, P=0.031) and 2.59-fold (aOR 95% CI: 1.23-5.95) more likely to be associated with viraemia (12% vs. 2%, P=0.025). Conversely, the HRV-A infected cases were more likely to have radiographically confirmed pneumonia (46%) compared to HRV-C infected cases (36%, P=0.040) and HRV-A mono-infected cases were more likely to have hospital stay of >3 days (72%) than HRV-C mono-infected cases (54%, P=0.039). Conclusion: HRV detection, especially among children 1-5 years of age, was associated with severe lower respiratory tract infection; however, HRV detection was ubiquitous with a high degree of genetic diversity among both cases and controls. Thus the true etiologic role of HRV during childhood disease, especially among infants, remains uncertain. Nonetheless, HRV nasopharyngeal viral loads ≥4log10 copies/mL in conjunction with HRV viraemia are potential markers for HRV-associated severe respiratory disease. Among cases, HRV-A was associated with radiographically confirmed pneumonia and generally more severe disease than HRV-C which was more associated with viraemia and wheezing disease.MT201

Falls prevention advice and visual feedback to those at risk of falling : study protocol for a pilot randomized controlled trial

Studies have shown that functional strength and balance exercises can reduce the risk of falling in older people if they are done on a regular basis. However, the repetitive nature of these exercises; combined with the inherent lack of feedback of progress may discourage seniors from exercising in the home, thereby rendering such an intervention ineffective. This study hypothesizes that the use of visual feedback and multimodal games will be more effective in encouraging adherence to home rehabilitation than standard care; thereby promoting independence and improving the quality of life in older adults at risk of falling

Exploring how drivers perceive spatial earcons in automated vehicles

Automated vehicles seek to relieve the human driver from primary driving tasks, but this substantially diminishes the connection between driver and vehicle compared to manual operation. At present, automated vehicles lack any form of continual, appropriate feedback to re-establish this connection and offer a feeling of control. We suggest that auditory feedback can be used to support the driver in this context. A preliminary field study that explored how drivers respond to existing auditory feedback in manual vehicles was first undertaken. We then designed a set of abstract, synthesised sounds presented spatially around the driver, known as Spatial Earcons, that represented different primary driving sounds e.g. acceleration. To evaluate their effectiveness, we undertook a driving simulator study in an outdoor setting using a real vehicle. Spatial Earcons performed as well as Existing Vehicle Sounds during automated and manual driving scenarios. Subjective responses suggested Spatial Earcons produced an engaging driving experience. This paper argues that entirely new synthesised primary driving sounds, such as Spatial Earcons, can be designed for automated vehicles to replace Existing Vehicle Sounds. This creates new possibilities for presenting primary driving information in automated vehicles using auditory feedback, in order to re-establish a connection between driver and vehicle

A comparison of artificial driving sounds for automated vehicles

As automated vehicles currently do not provide sufficient feedback relating to the primary driving task, drivers have no assurance that an automated vehicle has understood and can cope with upcoming traffic situations [16]. To address this we conducted two user evaluations to investigate auditory displays in automated vehicles using different types of sound cues related to the primary driving sounds: acceleration, deceleration/braking, gear changing and indicating. Our first study compared earcons, speech and auditory icons with existing vehicle sounds. Our findings suggested that earcons were an effective alternative to existing vehicle sounds for presenting information related to the primary driving task. Based on these findings a second study was conducted to further investigate earcons modulated by different sonic parameters to present primary driving sounds. We discovered that earcons containing naturally mapped sonic parameters such as pitch and timbre were as effective as existing sounds in a simulated automated vehicle

Using thermal stimuli to enhance photo-sharing in social media

Limited work has been undertaken to show how the emotive ability of thermal stimuli can be used for interaction purposes. One potential application area is using thermal stimuli to influence emotions in images shared online such as social media platforms. This paper presents a two-part study, which examines how the documented emotive property of thermal stimuli can be applied to enhance social media images. Participants in part-one supplied images from their personal collection or social media profiles, and were asked to augment each image with thermal stimuli based on the emotions they wanted to enhance or reduce. Part-one participants were interviewed to understand the effects they wanted augmented images to have. In part-two, these augmented images were perceived by a different set of participants in a simulated social media interface. Results showed strong agreement between the emotions augmented images were designed to evoke and the emotions they actually evoked as perceived by part-two participants. Participants in part-one selected thermal stimuli augmentation intended to modulate valence and arousal in images as a way of enhancing the realism of the images augmented. Part-two results indicate this was achieved as participants perceived thermal stimuli augmentation reduced valence in negative images and modulated valence and arousal in positive images

Using thermal stimuli to influence affect in different picture display sizes

The ability of images to evoke emotions in people has been well documented in previous research, as well as the differences in the emotional perception of images when viewed on different-sized screens and device types. The ability of thermal stimuli to evoke emotions in people when used for media augmentation has also been examined. However little is known about how thermal stimuli can be used to enhance or reduce affect in images with varying emotional properties displayed in different sizes or on different devices. To the best of our knowledge no work has been conducted to investigate if there is any difference in the effect thermal augmentation has on images displayed in different sizes on different device types. This paper presents two user studies to address this research gap. Study 1 explored the effect thermal stimulation has on images displayed in different sizes. Images were displayed in sizes corresponding to the full screen display of a laptop, tablet and mobile phone. In study 2 we examined whether the actual presentation device (tablet and mobile) plays a role in the emotional perception of images displayed on mobile devices. Results showed that thermal augmentation was most effective in modulating emotions in small-sized pictures (427x240 pixels display size) and pictures displayed on a mobile phone. Thermal stimuli also reduced emotions in medium display sizes (corresponding to the full screen display of a tablet)

Towards quantifying the impact of non-uniform information access in collaborative information retrieval

The majority of research into Collaborative Information Retrieval (CIR) has assumed a uniformity of information access and visibility between collaborators. However in a number of real world scenarios, information access is not uniform between all collaborators in a team e.g. security, health etc. This can be referred to as Multi-Level Collaborative Information Retrieval (MLCIR). To the best of our knowledge, there has not yet been any systematic investigation of the effect of MLCIR on search outcomes. To address this shortcoming, in this paper, we present the results of a simulated evaluation conducted over 4 different non-uniform information access scenarios and 3 different collaborative search strategies. Results indicate that there is some tolerance to removing access to the collection and that there may not always be a negative impact on performance. We also highlight how different access scenarios and search strategies impact on search outcomes